Indication
Sobicoat® is indicated in the management of metabolic acidosis associated with chronic kidney disease, in the normalisation of systemic, gastric and urinary alkali levels, and as replacement therapy in severe diarrhoea with substantial GI bicarbonate loss. Sodium bicarbonate is also used to increase urinary pH to enhance the solubility of certain weak acids (e.g., cystine, sulfonamides, uric acid), in haemolytic reactions requiring urinary alkalinisation, and as add-on therapy in hyperkalaemia to induce cellular uptake of potassium.
Mechanism of action
Sodium bicarbonate replenishes circulating bicarbonate, correcting metabolic acidosis and supporting acid-base homeostasis. The enteric coating of Sobicoat® is the differentiator - it may prevent dose-dumping in the stomach, improving GI tolerance and reducing the belching, bloating and other side effects commonly seen with conventional sodium-bicarbonate tablets in CKD patients.
Strengths
- •500 mg enteric-coated tablet
Composition
Each enteric-coated Sobicoat® tablet contains Sodium Bicarbonate U.S.P. 500 mg.
Presentation
Blister pack of 10 tablets in one strip, 10 strips in a box.
For Healthcare Professionals
Dosing varies with biochemical parameters: Sodium Bicarbonate from 325 mg up to 2,000 mg once-to-four-times daily; cumulative daily dose can extend to 16 g in selected conditions. Monitor serum bicarbonate, sodium and blood pressure during therapy.
This section is intended for use by registered medical practitioners only. All clinical decisions remain the prescriber's responsibility and should be informed by the current approved product label.
Notes for patients & caregivers
Take whole - do not crush or chew. The enteric coating is what protects you from the stomach upset usually seen with sodium bicarbonate. Follow the schedule your nephrologist gives you.
These notes are for general awareness only and are not a substitute for medical advice. Please follow your treating physician's instructions and the directions on the dispensed product.
Storage
Store below 25°C. Keep tightly closed and protected from moisture.
Important
- • Sobicoat® is a prescription medicine. It must only be used on the advice of a registered medical practitioner.
- • Always refer to the current approved Indian product label / package insert for definitive prescribing information.
- • If you experience any quality or safety concern, please contact us or write to info@vyapitus.com.